250649-13-9
Chemical Structure
NNC 11-1607
- CAS No.: 250649-13-9
- Formula:C30H32N6O2S2
- Molecular Weight:572.74
IUPAC Name: 1,3-bis(3-((4-((S)-quinuclidin-3-yl)-1,2,5-thiadiazol-3-yl)oxy)prop-1-yn-1-yl)benzene
InChIKey: TYLFZULSDOOCRC-CLJLJLNGSA-N
SMILES: C1(C#CCOC2=NSN=C2[C@@H]3CN4CCC3CC4)=CC=CC(C#CCOC5=NSN=C5[C@@H]6CN7CCC6CC7)=C1
Biological Activity: NNC 11-1607 is a selective M1/M4 muscarinic acetylcholine receptor (mAChR) agonist. NNC 11-1607 inhibits Forskolin (HY-15371)-stimulated cAMP accumulation in Chinese hamster ovary cells expressing the human M2 or M4 mAChR. NNC 11-1607 is promising for research of central nervous system disorders, such as Alzheimer’s disease and schizophrenia[1].
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NNC 11-1607 | NNC 11-1607 is a selective M1/M4 muscarinic acetylcholine receptor (mAChR) agonist. NNC 11-1607 inhibits Forskolin (HY-15371)-stimulated cAMP accumulation in Chinese hamster ovary cells expressing the human M2 or M4 mAChR. NNC 11-1607 is promising for research of central nervous system disorders, such as Alzheimer’s disease and schizophrenia. | |||||||||||||||||||||
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Keywords