2562329-14-8
2562329-14-8
Chemical Structure
Cdc7-IN-18
- CAS No.: 2562329-14-8
- Formula:C19H21N5OS
- Molecular Weight:367.47
IUPAC Name: (R)-8-(quinuclidin-2-yl)-2,4,5,6-tetrahydropyrazolo[4'',3'':3',4']cyclohepta[1',2':4,5]thieno[3,2-d]pyrimidin-10(7H)-one
InChIKey: MJWWMBBHELJWLE-CQSZACIVSA-N
SMILES: O=C1C2=C(NC([C@]3([H])N4CCC(CC4)C3)=N1)C5=C(C6=CNN=C6CCC5)S2
Biological Activity: Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].
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Cdc7-IN-18 | Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells. | |||||||||||||||||||||
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References
Keywords
