2562351-92-0
Chemical Structure
BTK-IN-25
- CAS No.: 2562351-92-0
- Formula:C28H27F2N3O5
- Molecular Weight:523.53
InChIKey: KRLUJQPLADLCAK-AEFFLSMTSA-N
SMILES: O=C(C1=C(C=C(C=C1)OC2=C(C=CC=C2)F)F)C3=CNC4=NC=C(OCC)C(N[C@@H]5CC[C@H](OC5)CO)=C34
Biological Activity: BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM[1].
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BTK-IN-25 | BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM. | |||||||||||||||||||||
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Keywords