2591197-83-8
2591197-83-8
Chemical Structure
Phthalimidinoglutarimide-piperidine-NH2
- CAS 番号: 2591197-83-8
- Formula:C18H22N4O3
- Molecular Weight:342.39
InChIKey: JZNXDRCANQHAFC-UHFFFAOYSA-N
SMILES: O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)N)=C3)C2)=O)=O
Biological Activity: Phthalimidinoglutarimide-piperidine-NH2 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Phthalimidinoglutarimide-piperidine-NH2 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Phthalimidinoglutarimide-piperidine-NH2 | Phthalimidinoglutarimide-piperidine-NH2 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Phthalimidinoglutarimide-piperidine-NH2 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules. | |||||||||||||||||||||
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