2601734-99-8
Chemical Structure
SIRT6 activator 12q
- CAS No.: 2601734-99-8
- Formula:C31H22N2O2
- Molecular Weight:454.52
IUPAC Name: N-benzhydryl-2-(benzofuran-2-yl)quinoline-4-carboxamide
InChIKey: JNULQPRWYHVXHT-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC3=C(C=CC=C3)O2)=NC4=C1C=CC=C4)NC(C5=CC=CC=C5)C6=CC=CC=C6
Biological Activity: SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SIRT6 activator 12q | 99.83% | SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity. | ||||||||||||||||||||
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Keywords
