1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Sirtuin
  4. SIRT6 Isoform
  5. SIRT6 Activator

SIRT6 Activator

SIRT6 Activators (2):

Cat. No. Product Name Effect Purity
  • HY-115453
    Activator 99.06%
    UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM.
  • HY-148712
    SIRT6 activator 12q
    Activator 98.01%
    SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity.