2634816-13-8
Chemical Structure
ERK1/2 inhibitor 6
- CAS No.: 2634816-13-8
- Formula:C27H29ClFN7O5
- Molecular Weight:586.01
IUPAC Name: (R)-2-(6-(5-chloro-2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)-4-oxopyrrolo[2,1-f][1,2,4]triazin-3(4H)-yl)-N-((S)-1-(3-fluoro-5-methoxyphenyl)-2-hydroxyethyl)propanamide
InChIKey: GJSHRKCWNUHGOU-IVZQSRNASA-N
SMILES: O=C1C2=CC(C3=NC(NC4CCOCC4)=NC=C3Cl)=CN2N=CN1[C@H](C)C(N[C@@H](C5=CC(OC)=CC(F)=C5)CO)=O
Biological Activity: ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 6 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021063335A1, compound 1)[1].
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ERK1/2 inhibitor 6 | ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 6 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021063335A1, compound 1). | |||||||||||||||||||||
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Keywords
