2648556-92-5
Chemical Structure
DGKα-IN-2
- CAS No.: 2648556-92-5
- Formula:C23H22F3N3O4
- Molecular Weight:461.43
InChIKey: AETHHGASMIIOSO-UHFFFAOYSA-N
SMILES: O=C(C1=C(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(F)F)C4=C(C=CC=C4)N(C)C1=O)N
Biological Activity: DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
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DGKα-IN-2 | 98.83% | DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study. | ||||||||||||||||||||
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Keywords