2663850-40-4
Chemical Structure
DNA-PK-IN-1
- CAS No.: 2663850-40-4
- Formula:C23H26N8O2
- Molecular Weight:446.50
IUPAC Name: 9-(3-hydroxyadamantan-1-yl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one
InChIKey: LUNNHYMBXZPWBL-UHFFFAOYSA-N
SMILES: O=C1N(C)C2=CN=C(NC3=CN4C(C=C3C)=NC=N4)N=C2N1C5(CC6C7)CC7(O)CC(C6)C5
Biological Activity: DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021136463A1, compound 1)[1].
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DNA-PK-IN-1 | DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-dependent protein kinase (DNA-PK) is a DNA-PK enzyme complex composed of Ku70/Ku80 heterodimer and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK-IN-1 has the potential for the research of cancer diseases (extracted from patent WO2021136463A1, compound 1). | |||||||||||||||||||||
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