2670380-82-0
2670380-82-0
Chemical Structure
ZG1077
- CAS No.: 2670380-82-0
- Formula:C33H33F2N5O5S
- Molecular Weight:649.71
IUPAC Name: 4-((2S,5R)-4-acryloyl-2,5-dimethylpiperazin-1-yl)-1-(2-cyclobutyl-6-(methylsulfonyl)phenyl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)pyrido[2,3-d]pyrimidin-2(1H)-one
InChIKey: SVGWLNVYDOKOFN-MOPGFXCFSA-N
SMILES: O=S(C)(C1=C(N(C2=C(C(N3[C@H](CN([C@@H](C3)C)C(C=C)=O)C)=N4)C=C(C(C5=C(F)C=CC=C5O)=N2)F)C4=O)C(C6CCC6)=CC=C1)=O
Biological Activity: ZG1077 is a covalent KRAS G12C inhibitor. ZG1077 can be used in the research of non-small cell lung cancer (NSCLC)[1].
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ZG1077 | ZG1077 is a covalent KRAS G12C inhibitor. ZG1077 can be used in the research of non-small cell lung cancer (NSCLC). | |||||||||||||||||||||
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References
Keywords
