2698339-21-6
Chemical Structure
N-(PEG1-acid)-L-Lysine-amido-Mal
- CAS No.: 2698339-21-6
- Formula:C18H28N4O7
- Molecular Weight:412.44
InChIKey: JYARUYKRCXJJKC-UHFFFAOYSA-N
SMILES: O=C(CCOCCC(NCCCCC(C(NCCN1C(C=CC1=O)=O)=O)N)=O)O
Biological Activity: N-(PEG1-acid)-L-Lysine-amido-Mal is a PEG based linker with terminal malimide and carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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N-(PEG1-acid)-L-Lysine-amido-Mal | N-(PEG1-acid)-L-Lysine-amido-Mal is a PEG based linker with terminal malimide and carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | |||||||||||||||||||||
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Keywords
