2715222-97-0
Chemical Structure
Antimalarial agent 8
- CAS No.: 2715222-97-0
- Formula:C22H21Cl3N4O
- Molecular Weight:463.79
IUPAC Name: 1-(3,4-dichlorophenyl)-8-methyl-N-(2-(methylamino)ethyl)-9H-pyrido[3,4-b]indole-3-carboxamide hydrochloride
InChIKey: VFUXYPUQCPMVGZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(NC3=C2C=CC=C3C)C(C4=CC(Cl)=C(Cl)C=C4)=N1)NCCNC.Cl
Biological Activity: Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria[1].
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Antimalarial agent 8 | Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria. | |||||||||||||||||||||
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Keywords