2734846-19-4
Chemical Structure
DNA-PK-IN-3
- CAS No.: 2734846-19-4
- Formula:C19H19N9O
- Molecular Weight:389.41
IUPAC Name: N-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-9-(tetrahydro-2H-pyran-4-yl)-9H-imidazo[2,1-f]purin-2-amine
InChIKey: FONYQGUKTNGBHC-UHFFFAOYSA-N
SMILES: CC1=CC2=NC=NN2C=C1NC3=NC=C4C(N(C5CCOCC5)C6=NC=CN64)=N3
Biological Activity: DNA-PK-IN-3 is a potent inhibitor of DNA-PK. DNA-PK-IN-3 synergistically enhances the effect of radiotherapy and chemotherapy and effectively inhibits tumor growth. DNA-PK-IN-3 also effectively reduces the damage to normal cells and reducing side effects. DNA-PK-IN-3 has the potential for the research of cancer disease (extracted from patent WO2021213460A1, compound 4)[1].
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DNA-PK-IN-3 | DNA-PK-IN-3 is a potent inhibitor of DNA-PK. DNA-PK-IN-3 synergistically enhances the effect of radiotherapy and chemotherapy and effectively inhibits tumor growth. DNA-PK-IN-3 also effectively reduces the damage to normal cells and reducing side effects. DNA-PK-IN-3 has the potential for the research of cancer disease (extracted from patent WO2021213460A1, compound 4). | |||||||||||||||||||||
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