2738381-94-5
Chemical Structure
P2Y1/P2Y12 antagonist-1
- CAS No.: 2738381-94-5
- Formula:C22H18N4O3
- Molecular Weight:386.40
InChIKey: AQVZLXOFKCFLKL-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(CON2C(C3=CC(C#N)=CC=C3)=NC(C)=C2C(OCC)=O)C=C1
Biological Activity: P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model.
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P2Y1/P2Y12 antagonist-1 | 99.87% | P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model. | ||||||||||||||||||||
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Keywords