2747133-37-3

EGFR-IN-23 Chemical Structure
2747133-37-3

Chemical Structure

EGFR-IN-23

  • CAS No.: 2747133-37-3
  • Formula:C36H44BrN10O3P
  • Molecular Weight:775.68

IUPAC Name: (6-((2-((4-(4-((1,4-oxazepan-4-yl)methyl)piperidin-1-yl)-2-methoxy-5-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-5-bromopyrimidin-4-yl)amino)quinoxalin-5-yl)dimethylphosphine oxide

InChIKey: JKILGRCOKYPKGD-UHFFFAOYSA-N

SMILES: CN1N=CC(C2=C(N3CCC(CN4CCOCCC4)CC3)C=C(OC)C(NC5=NC=C(Br)C(NC6=CC=C7N=CC=NC7=C6P(C)(C)=O)=N5)=C2)=C1

Biological Activity: EGFR-IN-23 is a potent EGFR TKI (tyrosine kinase inhibitor) with an IC50 of 8.05 nM for BaF3/EGFR-DEL19/T790M/C797S cell (WO2021244502A1, compound 8)[1].

Cat. No. Product Name Purity Description Pricing
HY-142680 		EGFR-IN-23 EGFR-IN-23 is a potent EGFR TKI (tyrosine kinase inhibitor) with an IC50 of 8.05 nM for BaF3/EGFR-DEL19/T790M/C797S cell (WO2021244502A1, compound 8).
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