2758876-18-3
Chemical Structure
Amino-PEG4-bis-PEG3-N3
- CAS No.: 2758876-18-3
- Formula:C36H70N10O15
- Molecular Weight:883.00
IUPAC Name: 3,3'-((2-(1-amino-3,6,9,12-tetraoxapentadecan-15-amido)propane-1,3-diyl)bis(oxy))bis(N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)propanamide)
InChIKey: AUWMMDYTNHESTC-UHFFFAOYSA-N
SMILES: O=C(CCOCCOCCOCCOCCN)NC(COCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)COCCC(NCCOCCOCCOCCN=[N+]=[N-])=O
Biological Activity: Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Amino-PEG4-bis-PEG3-N3 | Amino-PEG4-bis-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG4-bis-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
