2759918-83-5
Chemical Structure
Dolastatinol
- CAS No.: 2759918-83-5
- Formula:C43H70N6O7S
- Molecular Weight:815.12
IUPAC Name: (R)-2-((R)-2-(dimethylamino)-3-methylbutanamido)-N-((3S,4S,5R)-1-((R)-2-((1S,2S)-3-(((S)-1-(4-(hydroxymethyl)thiazol-2-yl)-2-phenylethyl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide
InChIKey: NSIGQNDUOSWNPO-RVXIVFAASA-N
SMILES: OCC1=CSC([C@H](CC2=CC=CC=C2)NC([C@@H](C)[C@@H]([C@]3([H])N(CCC3)C(C[C@H](OC)[C@H]([C@H](C)CC)N(C)C([C@@H](C(C)C)NC([C@H](N(C)C)C(C)C)=O)=O)=O)OC)=O)=N1
Biological Activity: Dolastatinol is a synthetic analog of dolastatin 10 and low nanomolar inhibitor of tubulin polymerization.
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Dolastatinol | Dolastatinol is a synthetic analog of dolastatin 10 and low nanomolar inhibitor of tubulin polymerization. | |||||||||||||||||||||
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Keywords