2760615-09-4
2760615-09-4
Chemical Structure
KPH2f
- CAS No.: 2760615-09-4
- Formula:C24H16N3NaO2S
- Molecular Weight:433.46
IUPAC Name: sodium 2-(((3-((4-cyanonaphthalen-1-yl)amino)pyridin-4-yl)thio)methyl)benzoate
InChIKey: VFQCYGPPRZHSKX-UHFFFAOYSA-M
SMILES: N#CC1=C2C=CC=CC2=C(C=C1)NC3=C(C=CN=C3)SCC4=CC=CC=C4C(O[Na])=O
Biological Activity: KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
KPH2f | 99.22% | KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
