2766583-86-0
Chemical Structure
Finbosertib
Synonym(s): ALK5-IN-85
- CAS No.: 2766583-86-0
- Formula:C33H32FN7O3
- Molecular Weight:593.65
IUPAC Name: 2-(piperazin-1-yl)ethyl 3-fluoro-5-(2-(3-(6-methylpyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazol-1-yl)acetamido)benzoate
InChIKey: IULPVLPJSYRUDQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(NC(CN2N=C(C(C3=C4C=CC=CC4=NC=C3)=C2)C5=CC=CC(C)=N5)=O)=CC(F)=C1)OCCN6CCNCC6
Biological Activity: Finbosertib (ALK5-IN-85) (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 of <100 nM. Finbosertib can be used for respiratory diseases including idiopathic pulmonary fibrosis, asthma, COPD and lumg cancer, and dermal and ocular fibrotic conditions research[1].
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Finbosertib | Finbosertib (ALK5-IN-85) (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 of <100 nM. Finbosertib can be used for respiratory diseases including idiopathic pulmonary fibrosis, asthma, COPD and lumg cancer, and dermal and ocular fibrotic conditions research. | |||||||||||||||||||||
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