2770091-44-4
2770091-44-4
Chemical Structure
WNTinib
Synonym(s): APS-8-100-2
- CAS No.: 2770091-44-4
- Formula:C22H16F6N4O3
- Molecular Weight:498.38
InChIKey: URCPDENSDRVZDE-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1F)OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(C(F)(C(F)(F)F)F)C=C3
Biological Activity: WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenicWntsignaling by inhibiting KIT/MAPK and downstream EZH2 activation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WNTinib | 99.95% | WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenicWntsignaling by inhibiting KIT/MAPK and downstream EZH2 activation. | ||||||||||||||||||||
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References
Keywords
