2770246-10-9
Chemical Structure
HSD17B13-IN-42
- CAS No.: 2770246-10-9
- Formula:C23H14Cl2F3N3O4
- Molecular Weight:524.28
InChIKey: OPOOJYGHWHUUAK-UHFFFAOYSA-N
SMILES: O=C1C2=C(NC(C3=CC(Cl)=C(O)C(Cl)=C3)=O)C=CC=C2N=CN1CC4=CC=CC(OC(F)(F)F)=C4
Biological Activity: HSD17B13-IN-42 (compound 10)? is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-42? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].
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HSD17B13-IN-42 | HSD17B13-IN-42 (compound 10)? is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-42? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis). | |||||||||||||||||||||
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Keywords