2773925-66-7
Chemical Structure
Mu opioid receptor antagonist 3
- CAS No.: 2773925-66-7
- Formula:C25H28N2O4S
- Molecular Weight:452.57
IUPAC Name: N-((4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)thiophene-2-carboxamide
InChIKey: QWAXZSMUYRTIIN-QODBOBSJSA-N
SMILES: O[C@]12[C@H]3CC4=C5[C@@]1(CCN3CC6CC6)[C@H]([C@@H](CC2)NC(C7=CC=CS7)=O)OC5=C(O)C=C4
Biological Activity: Mu opioid receptor antagonist 3 (compound 26) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of 0.24 nM and an EC50 of 0.54 nM. Mu opioid receptor antagonist 3 has remarkable CNS antagonism against morphine, and precipitated fewer withdrawal symptoms than Naloxone. Mu opioid receptor antagonist 3 can be used for researching opioid use disorders (OUD)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Mu opioid receptor antagonist 3 | Mu opioid receptor antagonist 3 (compound 26) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of 0.24 nM and an EC50 of 0.54 nM. Mu opioid receptor antagonist 3 has remarkable CNS antagonism against morphine, and precipitated fewer withdrawal symptoms than Naloxone. Mu opioid receptor antagonist 3 can be used for researching opioid use disorders (OUD). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
