2839668-87-8
2839668-87-8
Chemical Structure
Thalidomide-PIP-(R)C-pyrrolidine-boc
- CAS No.: 2839668-87-8
- Formula:C27H35N5O6
- Molecular Weight:525.60
InChIKey: UFWICOASIOWTOH-OQHSHRKDSA-N
SMILES: O=C1NC(CCC1N2C(C3=C(C=CC(N4CCN(CC4)C[C@@H]5CN(CC5)C(OC(C)(C)C)=O)=C3)C2=O)=O)=O
Biological Activity: Thalidomide-PIP-(R)C-pyrrolidine-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-PIP-(R)C-pyrrolidine-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Thalidomide-PIP-(R)C-pyrrolidine-boc | Thalidomide-PIP-(R)C-pyrrolidine-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-PIP-(R)C-pyrrolidine-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules. | |||||||||||||||||||||
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Keywords
