2853605-24-8
Chemical Structure
cMCoFx1
- CAS No.: 2853605-24-8
- Formula:C146H232N52O44S6
- Molecular Weight:3612.12
SMILES: O=C1N2[C@@](CCC2)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@]3(CSSC[C@@]4(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@@]5(CSSC[C@@]1(NC(=O)[C@]([C@H](CC)C)(NC(=O)CNC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC6=CC=C(O)C=C6)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@](CSSC[C@@](C(=O)N7[C@](C(=O)NCC(=O)N[C@@H](C)C(=O)N5)(CCC7)[H])(NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC3=O)[H])(NC(=O)[C@H](CC8=CC=CC=C8)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC4=O)[H])[H])[H])[H])[H])[H])[H])[H])[H])[H]
Biological Activity: cMCoFx1 is a potent and selective FXIIa cyclic peptide inhibitor. cMCoFx1 has high binding affinity (KD: 900 pM) and inhibitory activity (Ki: 370 pM) for FXIIa. cMCoFx1 can effectively inhibit endogenous clotting pathways, and cMCoFx1 is stable in serum and non-cytotoxic[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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cMCoFx1 | cMCoFx1 is a potent and selective FXIIa cyclic peptide inhibitor. cMCoFx1 has high binding affinity (KD: 900 pM) and inhibitory activity (Ki: 370 pM) for FXIIa. cMCoFx1 can effectively inhibit endogenous clotting pathways, and cMCoFx1 is stable in serum and non-cytotoxic. | |||||||||||||||||||||
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Keywords
