2857862-25-8

FGFR4-IN-10 Chemical Structure
2857862-25-8

Chemical Structure

FGFR4-IN-10

  • CAS No.: 2857862-25-8
  • Formula:C20H19F3N6O3
  • Molecular Weight:448.40

IUPAC Name: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-(2,2,2-trifluoroacetyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide

InChIKey: KRYAHOVOJWDVHJ-UHFFFAOYSA-N

SMILES: COCCNC1=C(C=NC(NC(N2CCCC3=CC=C(N=C32)C(C(F)(F)F)=O)=O)=C1)C#N

Biological Activity: FGFR4-IN-10 (compound 5a) is a potent and selective FGFR4 inhibitor with an IC50 value of 70.7 nM. FGFR4-IN-10 shows no inhibition against other FGFR family members, i.e. FGFR1, FGFR2 and FGFR3[1].

Cat. No. Product Name Purity Description Pricing
HY-146541 		FGFR4-IN-10 FGFR4-IN-10 (compound 5a) is a potent and selective FGFR4 inhibitor with an IC50 value of 70.7 nM. FGFR4-IN-10 shows no inhibition against other FGFR family members, i.e. FGFR1, FGFR2 and FGFR3.
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