288862-73-7
288862-73-7
Chemical Structure
CAY10435
- CAS No.: 288862-73-7
- Formula:C18H26N2O2
- Molecular Weight:302.41
IUPAC Name: 1-(oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
InChIKey: XUWBDQAPIZBSRY-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC(C1=NC2=NC=CC=C2O1)=O
Biological Activity: CAY10435 is a β-ketooxazapyridine, selective FAAH inhibitor with antimicrobial activity. CAY10435 binds non-competitively to the FAAH of Dictyostelium discoideum with a Kd value of 0.57 nM[1][2].
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CAY10435 | CAY10435 is a β-ketooxazapyridine, selective FAAH inhibitor with antimicrobial activity. CAY10435 binds non-competitively to the FAAH of Dictyostelium discoideum with a Kd value of 0.57 nM. | |||||||||||||||||||||
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References
- [1]. Hayes AC, et al. Identification of N-acylethanolamines in Dictyostelium discoideum and confirmation of their hydrolysis by fatty acid amide hydrolase. J Lipid Res. 2013 Feb;54(2):457-66. [Content Brief]
- [2]. Glaser ST, et al. Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain. J Pharmacol Exp Ther. 2006 Mar;316(3):1088-97. [Content Brief]
Keywords
