2891984-12-4
2891984-12-4
Chemical Structure
Anticancer agent 258
- CAS No.: 2891984-12-4
- Formula:C17H12F2N4
- Molecular Weight:310.30
InChIKey: DKWLKCTUPKUGSM-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=NN(C=C(N3C)C4=CC(F)=CC=C4)C3=N2)C=C1
Biological Activity: Anticancer agent 258 is an imidazo [1,2-B][1,2,4] triazol derivative. Anticancer agent 258 regulates the activity of nuclear receptors. Anticancer agent 258 has an EC50 of 63 nM against Nurr in N2A cells. Anticancer agent 258 has IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticancer agent 258 can be used in the study of cancer, metabolic diseases and neurological disorders[1].
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Anticancer agent 258 | Anticancer agent 258 is an imidazo [1,2-B][1,2,4] triazol derivative. Anticancer agent 258 regulates the activity of nuclear receptors. Anticancer agent 258 has an EC50 of 63 nM against Nurr in N2A cells. Anticancer agent 258 has IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticancer agent 258 can be used in the study of cancer, metabolic diseases and neurological disorders. | |||||||||||||||||||||
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References
Keywords
