2925588-01-6
Chemical Structure
PI3K/Akt/mTOR-IN-7
- CAS No.: 2925588-01-6
- Formula:C36H47NO7
- Molecular Weight:605.76
InChIKey: BHKRIKYMCRXCET-FHUFIDNLSA-N
SMILES: C[C@@]12[C@]3([H])[C@@](C[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O)=C[C@@H]4OC(/C=C/C6=C(C=CC=C6)[N+]([O-])=O)=O)C)([H])CC2)([H])O[C@]7(CC[C@H](CO7)C)[C@H]3C
Biological Activity: PI3K/Akt/mTOR-IN-7 is an AKT/mTOR and JAK2/STAT3 inhibitor. PI3K/Akt/mTOR-IN-7 restores p-Akt, p-mTOR, and p-STAT3 expression, reduces pro-apoptotic Caspase-3 mRNA expression. PI3K/Akt/mTOR-IN-7 reduces intracellular ROS accumulation and inhibits NO production. PI3K/Akt/mTOR-IN-7 can be used for research on stroke, Alzheimer's disease and Parkinson's disease[1].
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PI3K/Akt/mTOR-IN-7 | PI3K/Akt/mTOR-IN-7 is an AKT/mTOR and JAK2/STAT3 inhibitor. PI3K/Akt/mTOR-IN-7 restores p-Akt, p-mTOR, and p-STAT3 expression, reduces pro-apoptotic Caspase-3 mRNA expression. PI3K/Akt/mTOR-IN-7 reduces intracellular ROS accumulation and inhibits NO production. PI3K/Akt/mTOR-IN-7 can be used for research on stroke, Alzheimer's disease and Parkinson's disease. | |||||||||||||||||||||
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Keywords
