2945983-00-4
2945983-00-4
Chemical Structure
TS-IN-2
- CAS No.: 2945983-00-4
- Formula:C18H23N3O4S
- Molecular Weight:377.46
InChIKey: MJGWQHOWGVEFRN-UHFFFAOYSA-N
SMILES: S=C1OC(COC2=CC=C(CC=C)C=C2OC)=NN1CN3CCOCC3
Biological Activity: TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].
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TS-IN-2 | TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage. | |||||||||||||||||||||
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References
Keywords
