302343-10-8
Chemical Structure
Aurein 2.6
- CAS No.: 302343-10-8
- Formula:C77H133N19O19
- Molecular Weight:1629.00
InChIKey: YQOPYHDKGJJOGY-NYQNZTSUSA-N
SMILES: CC(C)C[C@@H](C(N)=O)NC([C@H](CO)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CN)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Aurein 2.6 is an antibiotic antimicrobial peptide. Aurein 2.6 is active against Gram-positive bacterial (MIC: 25, 25, 30, 25, 30 μM for M. luteus, S. aureus, S. epidermis, S. mutans, B. subtilis)[1][2].
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Aurein 2.6 | Aurein 2.6 is an antibiotic antimicrobial peptide. Aurein 2.6 is active against Gram-positive bacterial (MIC: 25, 25, 30, 25, 30 μM for M. luteus, S. aureus, S. epidermis, S. mutans, B. subtilis). | |||||||||||||||||||||
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- [1]. Rozek T, et al. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2. Eur J Biochem. 2000 Sep;267(17):5330-41. [Content Brief]
- [2]. Dennison SR, et al. PEGylation enhances the antibacterial and therapeutic potential of amphibian host defence peptides. Biochim Biophys Acta Biomembr. 2022 Feb 1;1864(1):183806. [Content Brief]
Keywords
