3024991-82-7
3024991-82-7
Chemical Structure
K-Ras-IN-3
- CAS 番号: 3024991-82-7
- Formula:C34H29F6N5O4
- Molecular Weight:685.62
InChIKey: PFJYGEUPHPKJBL-NAIKRYSESA-N
SMILES: OC(C(F)(F)F)=O.CN([C@@H]1[C@H](C1)F)C2=NC(OCC34N(CCC4)CC(C3)=C)=NC5=C2C=NC(C6=CC(O)=CC7=C6C(C#C)=C(F)C=C7)=C5F
Biological Activity: K-Ras-IN-3 (compound 3) is a potent GDP-KRAS G12V inhibitor with an IC50 value of 0.371 nM. K-Ras-IN-3 has the potential for the research of cancer[1].
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K-Ras-IN-3 | K-Ras-IN-3 (compound 3) is a potent GDP-KRAS G12V inhibitor with an IC50 value of 0.371 nM. K-Ras-IN-3 has the potential for the research of cancer. | |||||||||||||||||||||
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References
Keywords
