3026984-15-3
3026984-15-3
Chemical Structure
hAChE/hBACE-1-IN-3
- CAS No.: 3026984-15-3
- Formula:C25H31N3O3
- Molecular Weight:421.53
InChIKey: MHFAWVHGIRXFHE-UHFFFAOYSA-N
SMILES: O=C(NCCC1CCN(CC2=CC=CC=C2)CC1)C3=CC4=C(N3)C=C(OC)C(OC)=C4
Biological Activity: hAChE/hBACE-1-IN-3 (Compound 23a) is a mixed-type inhibitor of hAChE and hBACE-1 with IC50 values of 0.32 μM and 0.39 μM, respectively, Ki values of 0.26 μM and 0.46 μM, respectively. hAChE/hBACE-1-IN-3 can penetrate the blood-brain barrier[1].
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hAChE/hBACE-1-IN-3 | hAChE/hBACE-1-IN-3 (Compound 23a) is a mixed-type inhibitor of hAChE and hBACE-1 with IC50 values of 0.32 μM and 0.39 μM, respectively, Ki values of 0.26 μM and 0.46 μM, respectively. hAChE/hBACE-1-IN-3 can penetrate the blood-brain barrier. | |||||||||||||||||||||
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References
Keywords
