3031098-46-8
3031098-46-8
Chemical Structure
CYP11B1-IN-2
- CAS No.: 3031098-46-8
- Formula:C21H19N5O2
- Molecular Weight:373.41
IUPAC Name: 3-bromo-5-fluoro-6-iodo-2-methylbenzoic acid
InChIKey: RGHYMBULABJHQT-OKNMBPCOSA-N
SMILES: [H][C@@]12C(C3=CC=CN=C3)=NO[C@@]1([C@@H]4C[C@H]2CC4)C(NC5=CC6=C(C=C5)NN=C6)=O
Biological Activity: CYP11B1-IN-2 (compound 7aa) is an orally active, potent and selective CYP11B1 inhibitor, with IC50 values of 9 nM and 25 nM for human CYP11B1 and rat CYP11B1, respectively. CYP11B1-IN-2 can be used for the research of diseases caused by excessive cortisol[1].
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CYP11B1-IN-2 | CYP11B1-IN-2 (compound 7aa) is an orally active, potent and selective CYP11B1 inhibitor, with IC50 values of 9 nM and 25 nM for human CYP11B1 and rat CYP11B1, respectively. CYP11B1-IN-2 can be used for the research of diseases caused by excessive cortisol. | |||||||||||||||||||||
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References
Keywords
