3031463-59-6
3031463-59-6
Chemical Structure
UAB116
- CAS No.: 3031463-59-6
- Formula:C25H38O2
- Molecular Weight:370.57
InChIKey: USDOYFQDHIMGBQ-NUXCVKLASA-N
SMILES: CCC(C)C(CCC/C1=C\C(C)=C/C=C/C(C)=C/C(O)=O)=C1CCC(C)C
Biological Activity: UAB116 is a Liver X Receptor (LXR)/Retinoid X Receptor (RXR) agonist. UAB116 can decreases metastatic phenotype in hepatoblastoma by inhibiting the Wnt/β-Catenin pathway via upregulation of TRIM29. UAB116 can reduce proliferation, stemness and invasiveness of metastatic hepatoblastoma cells[1].
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UAB116 | UAB116 is a Liver X Receptor (LXR)/Retinoid X Receptor (RXR) agonist. UAB116 can decreases metastatic phenotype in hepatoblastoma by inhibiting the Wnt/β-Catenin pathway via upregulation of TRIM29. UAB116 can reduce proliferation, stemness and invasiveness of metastatic hepatoblastoma cells. | |||||||||||||||||||||
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References
Keywords
