3032997-16-0
3032997-16-0
Chemical Structure
CDK1-IN-4
- CAS No.: 3032997-16-0
- Formula:C26H24ClN5S
- Molecular Weight:474.02
IUPAC Name: 4-(4-benzylphthalazin-1-yl)-N-(3-chlorophenyl)piperazine-1-carbothioamide
InChIKey: ZNJIRQMCOQXGAV-UHFFFAOYSA-N
SMILES: S=C(N1CCN(C2=NN=C(CC3=CC=CC=C3)C4=C2C=CC=C4)CC1)NC5=CC=CC(Cl)=C5
Biological Activity: CDK1-IN-4 (10d) is a selective CDK1 inhibitor with IC50s of 44.52, 624.93 and 135.22 nM for CDK1, CDK2 and CDK5, respectively. CDK1-IN4 inhibits the growth of cancer cells by affecting cell cycle. CDK1-IN-4 can be used for the research of cancer[1].
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CDK1-IN-4 | CDK1-IN-4 (10d) is a selective CDK1 inhibitor with IC50s of 44.52, 624.93 and 135.22 nM for CDK1, CDK2 and CDK5, respectively. CDK1-IN4 inhibits the growth of cancer cells by affecting cell cycle. CDK1-IN-4 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
