3035023-20-9
3035023-20-9
Chemical Structure
RB-07-16
- CAS No.: 3035023-20-9
- Formula:C21H19F3N6O7P2
- Molecular Weight:586.35
InChIKey: WUZPMXBCFREYEO-UHFFFAOYSA-N
SMILES: CN1N=CC2=C1N=C(C3=CC=CC(C(NC4=CC=C(C(F)(F)F)C=C4)=O)=C3)N=C2NC(P(O)(O)=O)P(O)(O)=O
Biological Activity: RB-07-16 is a C6-PyraP-BP inhibitor of human geranylammate pyrophosphate synthase (hGGPPS). RB-07-16 has antitumor activity[1].
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RB-07-16 | RB-07-16 is a C6-PyraP-BP inhibitor of human geranylammate pyrophosphate synthase (hGGPPS). RB-07-16 has antitumor activity. | |||||||||||||||||||||
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References
- [1]. Rebecca Boutin, et al. Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer. J Med Chem. 2023, 66, 23. [Content Brief]
Keywords
