3038489-04-9
3038489-04-9
Chemical Structure
PLK1-IN-6
- CAS No.: 3038489-04-9
- Formula:C28H37N9O3
- Molecular Weight:547.65
IUPAC Name: (R)-8-cyclopentyl-7-ethyl-2-((2-methoxy-4-(5-(piperazin-1-ylmethyl)-1,2,4-oxadiazol-3-yl)phenyl)amino)-5-methyl-7,8-dihydropteridin-6(5H)-one
InChIKey: CQQFCBITQKNHPX-OAQYLSRUSA-N
SMILES: CC[C@@H]1C(N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C5=NOC(CN6CCNCC6)=N5)OC)C)=O
Biological Activity: PLK1-IN-6 is a potent and selective PLK1 inhibitor, with an IC50 of 0.45 nM. PLK1-IN-6 shows significant anti-proliferative activities against cancer cells[1].
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PLK1-IN-6 | PLK1-IN-6 is a potent and selective PLK1 inhibitor, with an IC50 of 0.45 nM. PLK1-IN-6 shows significant anti-proliferative activities against cancer cells. | |||||||||||||||||||||
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References
Keywords
