3041994-96-8
3041994-96-8
Chemical Structure
CDK-IN-13
- CAS No.: 3041994-96-8
- Formula:C23H27N7O3
- Molecular Weight:449.51
InChIKey: UCBXGDNAAUVBDT-GOSISDBHSA-N
SMILES: CCN1C=NC2=C(N=C(N=C21)N3CCOC[C@H]3CCO)NCC4=CN=C(C=C4)C5=COC=C5
Biological Activity: CDK-IN-13 (compound 32E) is a potent and selective inhibitor of CDK12/cyclinK with an IC50 of 3 nM. CDK-IN-13 inhibits the growth of the HER2-positive breast cancer cell lines[1].
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CDK-IN-13 | CDK-IN-13 (compound 32E) is a potent and selective inhibitor of CDK12/cyclinK with an IC50 of 3 nM. CDK-IN-13 inhibits the growth of the HER2-positive breast cancer cell lines. | |||||||||||||||||||||
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References
Keywords
