3049369-11-8
3049369-11-8
Chemical Structure
LLW-018
- CAS No.: 3049369-11-8
- Formula:C35H38Cl2N4O5S
- Molecular Weight:697.67
InChIKey: LZTKJONVMVAYAC-UHFFFAOYSA-N
SMILES: OCC(CO)NCC1=CC=C(NC2=NSC3=C2C=CC=C3C4=C(C)C(COC5=C(Cl)C=C(CNC(CO)CO)C=C5)=CC=C4)C(Cl)=C1
Biological Activity: LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. LLW-018 can interrupt PD-1/PD-L1 interaction with an IC50 value of 0.88 μM by cell-based PD-1/PD-L1 blockade bioassays. LLW-018 has the potential for immunotherapy research[1].
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LLW-018 | LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. LLW-018 can interrupt PD-1/PD-L1 interaction with an IC50 value of 0.88 μM by cell-based PD-1/PD-L1 blockade bioassays. LLW-018 has the potential for immunotherapy research. | |||||||||||||||||||||
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References
Keywords
