3056387-72-2
3056387-72-2
Chemical Structure
Hsp110/sGC-modulator-1
- CAS No.: 3056387-72-2
- Formula:C24H18ClF3N2O4
- Molecular Weight:490.86
InChIKey: KXYHYIDMUQJBBC-UHFFFAOYSA-N
SMILES: O=C(O)CCC1=CC=CC(NC(C2=CC(Cl)=CC=C2NC(C3=CC=C(C(F)(F)F)C=C3)=O)=O)=C1
Biological Activity: Hsp110/sGC-modulator-1 (compound 17i), an orally active Hsp110/sGC dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression[1].
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Hsp110/sGC-modulator-1 | 99.58% | Hsp110/sGC-modulator-1 (compound 17i), an orally active Hsp110/sGC dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression. | ||||||||||||||||||||
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References
Keywords
