3056563-44-8
3056563-44-8
Chemical Structure
NUDT5/14 antagonist 1
- CAS. Nr.: 3056563-44-8
- Formula:C23H24N6O
- Molecular Weight:400.48
InChIKey: KHLKLLMMPVSSQY-UHFFFAOYSA-N
SMILES: NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCN(CC5)C)=NC=N1
Biological Activity: NUDT5/14 antagonist 1 (Compound 9) is a selective, dual antagonist for nucleotide diphosphate kinase NUDT5 and NUDT14, with IC50 of 0.27 and 0.16 μM, respectively. NUDT5/14 antagonist 1 binds to Bruton’s tyrosine kinase (BTK) with an IC50 of 0.377 μM[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NUDT5/14 antagonist 1 | 99.69% | NUDT5/14 antagonist 1 (Compound 9) is a selective, dual antagonist for nucleotide diphosphate kinase NUDT5 and NUDT14, with IC50 of 0.27 and 0.16 μM, respectively. NUDT5/14 antagonist 1 binds to Bruton’s tyrosine kinase (BTK) with an IC50 of 0.377 μM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
