3082621-32-4
Chemical Structure
AcrB-IN-6
- CAS No.: 3082621-32-4
- Formula:C28H33BrN2O2
- Molecular Weight:509.48
IUPAC Name: 2-(7-((4-bromobenzyl)oxy)-3,3-dimethyl-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-1-(piperidin-1-yl)ethan-1-one
InChIKey: HPPQSWWOMWJQQN-UHFFFAOYSA-N
SMILES: O=C(N1CCCCC1)CN2C3=C(C4=C2C=C(OCC5=CC=C(Br)C=C5)C=C4)CC(C)(C)CC3
Biological Activity: AcrB-IN-6 is an effective AcrB inhibitor. AcrB-IN-6 The compound inhibits the function of bacterial multidrug efflux pumps, thereby significantly enhancing the antibacterial activity of various antibiotics. AcrB-IN-6 achieves 32-fold MIC reductions in wild-type E. coli BW25113. AcrB-IN-6 exhibits excellent synergistic antibacterial effects, low cytotoxicity and hemolytic properties. AcrB-IN-6 can be used for researching anti-resistant bacteria[1].
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AcrB-IN-6 | AcrB-IN-6 is an effective AcrB inhibitor. AcrB-IN-6 The compound inhibits the function of bacterial multidrug efflux pumps, thereby significantly enhancing the antibacterial activity of various antibiotics. AcrB-IN-6 achieves 32-fold MIC reductions in wild-type E. coli BW25113. AcrB-IN-6 exhibits excellent synergistic antibacterial effects, low cytotoxicity and hemolytic properties. AcrB-IN-6 can be used for researching anti-resistant bacteria. | |||||||||||||||||||||
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Keywords
