3099681-58-7
3099681-58-7
Chemical Structure
PARL-IN-2
- CAS No.: 3099681-58-7
- Formula:C22H23NO4
- Molecular Weight:365.42
InChIKey: DHXWXHIEOYCJLR-UHFFFAOYSA-N
SMILES: O=C(OCC1=CC=CC=C1)C2=CC=C(CN3C(C(CC)(CC)C3=O)=O)C=C2
Biological Activity: PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial intramembrane protease PARL with an EC50 value of 0.16 μM. PARL-IN-2 leads to a robust activation of the PINK1/Parkin pathway. PARL-IN-2 promotes PINK1/Parkin-dependent mitophagy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PARL-IN-2 | 99.80% | PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial intramembrane protease PARL with an EC50 value of 0.16 μM. PARL-IN-2 leads to a robust activation of the PINK1/Parkin pathway. PARL-IN-2 promotes PINK1/Parkin-dependent mitophagy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
