3100092-62-1
Chemical Structure
MKK7-JNK activator 1
- CAS No.: 3100092-62-1
- Formula:C17H12Br2INO
- Molecular Weight:533.00
InChIKey: QYNNAFHZBLVSFH-UHFFFAOYSA-N
SMILES: CC1=NC2=C(OCC3=CC=CC(I)=C3)C(Br)=CC(Br)=C2C=C1
Biological Activity: MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator. MKK7-JNK activator 1 effectively inhibits the proliferation and migration of MDA-MB-468 cells, induces G2/M phase arrest and caspase -dependent apoptosis (independent of ROS production). MKK7-JNK activator 1 significantly increases the levels of p-MKK7 and p-JNK, but does not affect p-ERK or p-p38. MKK7-JNK activator 1 can be used for the study of triple-negative breast cancer (TNBC)[1].
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MKK7-JNK activator 1 | 99.89% | MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator. MKK7-JNK activator 1 effectively inhibits the proliferation and migration of MDA-MB-468 cells, induces G2/M phase arrest and caspase -dependent apoptosis (independent of ROS production). MKK7-JNK activator 1 significantly increases the levels of p-MKK7 and p-JNK, but does not affect p-ERK or p-p38. MKK7-JNK activator 1 can be used for the study of triple-negative breast cancer (TNBC). | ||||||||||||||||||||
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Keywords
