310460-39-0
310460-39-0
Chemical Structure
CPYPP
- CAS No.: 310460-39-0
- Formula:C18H13ClN2O2
- Molecular Weight:324.76
IUPAC Name: (E)-4-((E)-3-(2-chlorophenyl)allylidene)-1-phenylpyrazolidine-3,5-dione
InChIKey: VVZJFICTTKPNCK-KVDBUQHUSA-N
SMILES: O=C(/C1=C\C=C\C2=CC=CC=C2Cl)NN(C3=CC=CC=C3)C1=O
Biological Activity: CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 µM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CPYPP | 99.80% | CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 µM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9. | ||||||||||||||||||||
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References
Keywords
