3122200-59-0
3122200-59-0
Chemical Structure
PDL1 degrader-1
- CAS No.: 3122200-59-0
- Formula:C22H25ClN2O4
- Molecular Weight:416.90
InChIKey: ORGPBGWSTWYXLM-UHFFFAOYSA-M
SMILES: COC1=C(C2=C[N+]3=C(C4=CC(OC)=C(C=C4CC3)OC)C=C2C=C1)OCCN.[Cl-]
Biological Activity: PDL1 degrader-1 is a palmatine-derived PD-L1 degrader. PDL1 degrader-1 interacts with and inhibits deubiquitinase CSN5, inducing PD-L1 Ub/proteasome-dependent degradation. PDL1 degrader-1 can be used for the research of non-small cell lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PDL1 degrader-1 | 95.25% | PDL1 degrader-1 is a palmatine-derived PD-L1 degrader. PDL1 degrader-1 interacts with and inhibits deubiquitinase CSN5, inducing PD-L1 Ub/proteasome-dependent degradation. PDL1 degrader-1 can be used for the research of non-small cell lung cancer. | ||||||||||||||||||||
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