3123220-86-7
3123220-86-7
Chemical Structure
PB2-IN-4
- CAS No.: 3123220-86-7
- Formula:C22H22FN9O
- Molecular Weight:447.47
InChIKey: ZLNDRVJVEVQTQG-GVSXRFJSSA-N
SMILES: N#CNC([C@H]1C2CCC(CC2)[C@@H]1NC3=C(C(C4CC4)=NC(C5=NNC6=C5C=NC=N6)=N3)F)=O
Biological Activity: PB2-IN-4 is a potent and orally effective PB2 inhibitor with an IC50 of 82 nM. PB2-IN-4 inhibits viral RNA polymerase activity and gene expression by binding to the PB2 protein, and alleviates the host inflammatory response. PB2-IN-4 can be used for research on influenza A virus[1].
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PB2-IN-4 | PB2-IN-4 is a potent and orally effective PB2 inhibitor with an IC50 of 82 nM. PB2-IN-4 inhibits viral RNA polymerase activity and gene expression by binding to the PB2 protein, and alleviates the host inflammatory response. PB2-IN-4 can be used for research on influenza A virus. | |||||||||||||||||||||
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