3125694-57-4

MET/PDGFRA-IN-2 Chemical Structure
3125694-57-4

Chemical Structure

MET/PDGFRA-IN-2

  • CAS No.: 3125694-57-4
  • Formula:C29H29N7O
  • Molecular Weight:491.59

InChIKey: KSSCDIVAUZWVFC-KPGMTVGESA-N

SMILES: CC(C1=CC=C(C=C1)CN2N=NC(COC3=CC=C(C=C3)/C=N/NC4=C5C=CC=CC5=NC=N4)=C2)(C)C

Biological Activity: MET/PDGFRA-IN-2 (compound 8h) is a MET and PDGFRA protein inhibitor. MET/PDGFRA-IN-2 induces cell apoptosis. MET/PDGFRA-IN-2 inhibits proliferation of MET-positive cells (IC50s: 9.7, 6.1, 12.0, 11.5, 8.6, 34.4 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, K562 cells respectively)[1].

Cat. No. Product Name Purity Description Pricing
HY-149511 		MET/PDGFRA-IN-2 MET/PDGFRA-IN-2 (compound 8h) is a MET and PDGFRA protein inhibitor. MET/PDGFRA-IN-2 induces cell apoptosis. MET/PDGFRA-IN-2 inhibits proliferation of MET-positive cells (IC50s: 9.7, 6.1, 12.0, 11.5, 8.6, 34.4 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, K562 cells respectively).
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