313964-19-1
Chemical Structure
HIF-2α-IN-3
- CAS No.: 313964-19-1
- Formula:C12H6ClN5O5
- Molecular Weight:335.66
IUPAC Name: N-(4-chloro-3-nitrophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine
InChIKey: PQZKMXPISWCLCU-UHFFFAOYSA-N
SMILES: O=[N+](C1=C(NC2=CC=C(Cl)C([N+]([O-])=O)=C2)C=CC3=NON=C31)[O-]
Biological Activity: HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α (HIF-2α), exhibits an IC50 of 0.4 µM and a KD of 1.1 µM. Anticancer agent[1].
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HIF-2α-IN-3 | 99.89% | HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α (HIF-2α), exhibits an IC50 of 0.4 µM and a KD of 1.1 µM. Anticancer agent. | ||||||||||||||||||||
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Keywords