318480-82-9
318480-82-9
Chemical Structure
SC-68376
- CAS No.: 318480-82-9
- Formula:C15H12N2O
- Molecular Weight:236.27
IUPAC Name: 2-methyl-4-phenyl-5-(pyridin-4-yl)oxazole
InChIKey: BHWCZLOXTLWZAQ-UHFFFAOYSA-N
SMILES: CC1=NC(C2=CC=CC=C2)=C(O1)C3=CC=NC=C3
Biological Activity: SC-68376 is a potent, reversible, ATP-competitive, and selective inhibitor of p38 MAP kinase inhibitor[1][2][3].
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SC-68376 | SC-68376 is a potent, reversible, ATP-competitive, and selective inhibitor of p38 MAP kinase inhibitor. | |||||||||||||||||||||
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References
- [1]. H. Bosch, et al. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors. US20030181411A1. 2005-12-07.
- [2]. Ermert M, et al. Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs. Lab Invest. 2003;83(3):333-347. [Content Brief]
- [3]. Kooijman R, et al. IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase. Cell Signal. 2003;15(12):1091-1098. [Content Brief]
Keywords
